Studies indicate that ingested custom oral cyanocobalamin tablets are ineffective in the treatment of allergic disease, perhaps because once ingested, they are directly metabolized in the liver. When B12 is delivered via injection or lozenge it passes throughout the bloodstream before arriving at the liver. It is during this first pass in its native form that hair and piece it is believed to exert its therapeutic custom effect. CLINICAL RESEARCH: "The World Health Organization (WHO) recognizes allergic rhinitis (hay fever), sinusitis, asthma,...conjunctivitis, urticaria, eczema, dermatitis (contact hair and atopic)...allergic and migraine headache...as piece diseases in which IgE-mediated allergy may be involved."1 In 1988, asthma and allergic rhinitis subjects were treated with B12. Total IgE, specific IgE and pulmonary lung functions custom and hair were taken at days 45, 150 and 180 from baseline. Eight of the 9 subjects had reduced IgE. 2 In 1989 open label studies at two sites in Riverside County, CA in 1989. Sixteen of the 17 piece subjects had lowered IgE levels from Day 0 to Day 30.3

Genentech custom and Novartis are hair developing an anti-IgE monoclonal antibody for asthma and allergic rhinitis. In December 1999 they announced positive study results. This is evidence that reducing IgE results in a reduction of symptoms associated with IgE-mediated allergic disease.13 For people who find they cannot adequately avoid piece the allergens, the symptoms often can be controlled with medications. custom Effective hair and piece medications custom that can be prescribed by a physician include antihistamines, topical nasal steroids, hair and cromolyn piece sodium - any of which can be used alone or in combination. Many effective antihistamines and decongestants also are available without a prescription. Click here for allergy medication online.

In custom 1990 study in San Diego, hair CA the 5 active subjects with allergic rhinitis had a lowered total serum IgE from Day 0 to Day 90 while 4 placebo subjects, (2 with allergic rhinitis, 1 with asthma piece and custom 1 with both), had flat or increased IgE levels.4 In hair a randomized, piece double-blind, custom placebo controlled study of symptoms and hair serum IgE levels in San Diego, CA in mid-1991, piece subjects had allergic rhinitis and/or asthma. Serum was drawn at Day 0 and Day 30. Seven of the 10 active treated subjects had a reduction in total serum IgE custom levels. In 10 placebo treated subjects, 5 had levels of total serum IgE that stayed the same (plus or minus 5%), 3 decreased and 2 increased.5 Statistical analysis of the open-label study hair as well as the double-blind randomized placebo controlled study have shown a significant piece effect of vitamin B12 in lowering serum IgE concentrations.